Genome Organization
1. List the functional elements needed for chromosomal replication and segregation.
State the function of these elements.
Define YAC.
2. Distinguish between unique and repetitive DNA.
Describe how these types of DNA are distributed in the genome and state their functions.
3. List the constituents of chromatin and state their functions.
Describe how chromatin forms a chromosome.
Define the terms: histone, nucleosome, chromatosome, scaffolding, SAR, heterochromatin and euchromatin.
4. Describe how and why chromatin is thought to restructure itself in order to regulate transcription.
5. List the characteristic features of the mitochondrial genome.
© Dr. Noel Sturm 2004